Henry del Vasto (died before 1141) was a son of Manfred del Vasto, margrave of Western Liguria, and brother of Adelaide, countess of Sicily (1089–1117) and Jerusalem (1112–1117).
He received Paternò and Butera in Sicily from either Roger I of Sicily or Adelaide during her regency after 1101. He also married Flandina, a daughter of Roger and his second wife, Eremburga of Mortain. His nephew, Roger II, named one of his sons Henry after the child's great uncle. He was the founder of the Mazzarino family.
According to Alexander of Telese, it was Henry's idea that Roger, who then ruled all of Southern Italy and Sicily, should have the title of king and rule in Palermo, where, he alleged, kings had ruled in the past. Roger was duly crowned in 1130.